Lost Dosage When Using CBD Edibles

The bioavailability of CBD when consumed as an edible can vary depending on a number of factors, including the individual’s metabolism, the specific product being used, and the amount of CBD consumed.

Bioavailability refers to the proportion of a substance (in this case, CBD) that is able to enter the bloodstream and be utilized by the body. When CBD is consumed as an edible, it must first be broken down and metabolized by the digestive system before it can be absorbed into the bloodstream. This process can be slower and less efficient compared to other methods of CBD ingestion, such as sublingual tinctures or inhalation.

Studies have shown that the bioavailability of CBD when consumed as an edible can range from 4% to 20%. This means that, on average, only a small proportion of the CBD consumed as an edible is actually absorbed into the bloodstream and utilized by the body.

One study published in the journal Pharmaceuticals found that the bioavailability of CBD when taken orally (such as with edibles) ranged from 6% to 20%, depending on the dose and formulation of the product. This is significantly lower compared to the bioavailability of inhaled CBD, which was found to be much higher at 11% to 45%.

The low bioavailability of CBD when consumed as an edible is due to several factors. One of the main reasons is that CBD is a lipophilic molecule, meaning that it is soluble in fats and oils but not water. This makes it difficult for the body to absorb CBD through the walls of the digestive system, which are primarily made up of water-based cells.

Additionally, the digestive system can break down and metabolize some of the CBD before it is able to be absorbed into the bloodstream. This means that a portion of the CBD may be lost before it can be utilized by the body.

Despite the lower bioavailability of CBD when consumed as an edible, many people still find edibles to be an effective way to consume CBD. The slower onset time and longer-lasting effects of edibles can be beneficial for certain conditions, such as chronic pain or anxiety. Additionally, many CBD edibles are formulated to contain higher doses of CBD, which can help compensate for any potential losses due to the digestive process.

Overall, while the bioavailability of CBD when consumed as an edible is lower compared to other methods of ingestion, it is still possible to achieve the desired effects with careful dosing and by choosing high-quality, well-formulated products. If you have any concerns about the bioavailability of CBD when consumed as an edible, you may wish to discuss your options with a healthcare provider or a knowledgeable CBD retailer.